"There have been several cases reported in which human venison eaters have contracted Creutzfeldt-Jakob disease (CJD), which, like chronic wasting disease, is a transmissible spongiform encephalopathy (TSE), but one that occurs naturally in humans.
Gambetti said that these cases seem to fit into known subtypes of CJD, but he added that the assumption that human cases from deer or elk would look different upon microscopic examination than ordinary CJD is just that - an assumption.
Most scientists believe all TSEs - CWD, CJD and mad cow disease in cattle - are all caused by a mutant protein called a prion.
Most scientists believe there is a strong barrier preventing prions from one species from infecting another. But 131 European beef eaters have contracted a variant of CJD caused by eating cattle suffering from mad cow disease, or bovine spongiform encephalopathy (BSE)."
That has sparked concern that other spongiform encephalopathies, including CWD, could jump to humans or livestock.
This is an article by Lou Kilzer