If you are using stiff, less forgiving, large diameter arrows the more drag the better as long as you are getting clearance. I am personally going to use a four fletch 3" vane on my indoor setup this year and I know in the past that Dee Wilde has shot 4-fletch in the past with great results. You just get a lowere profile with plenty of drag that way and it helps with clearing the cables and riser with the fletching.