Of course you could kill a moose with one. It is beyond me why in the world you want to use one. Being unable to get into close quarters seems rare with moose hunting so I really don't understand why you would risk it. Plenty of mechanicals are extremely tough, yet they all take a lot of pressure to push, and deploy blades compared to COCs. If I was going to spend the coin on a moose hunt, I would be using the best fixed blade money could buy. That would include, Iron Will, Day Six, or Valkyrie. If for some reason I just had to use a mechanical it would be the one from Evolution Outdoors with the steel ferrule.