I am hunting that situation with a crossbow. Perfect setup to shoot either dead on facing me or broadside. Quartering away shots are only rarely a possibility.
First year with 2 inch Rages I had runs of 6 feet, 100 yards, 50-60 yards and just over 200 yards. Those were three shots through the heart and the last one was just above the heart severing it loose from the lungs and almost completely loose in the chest. The next year One with a 3 blade Muzzy went 60 yards, One with a Rage went 60-80, Two with a Nap Spitfire Doublecross, both went about 40 yards.
This year I shot one NAP Spitfire Doublecross (double lung close behing the shoulder) and lost it. Another (double lung but well back, just a couple inches ahead of the diaphragm) with the same head managed to get almost a mile in a straight line.
I don't see enough predictability with what happens after the shot to say one head is better or worse.
Fortunately these are my neighbors and they've had their fill of everything being eaten and hitting them with cars so even those who'd rather I didn't shoot them will let me recover them without complaint. If I had to do this where I didn't know the people, I wouldn't. Out of those deer I have had five cross portions of mowed lawns. Fortunately no one saw them do it.
The last numbers I saw for Minnesota were something like 31 per cent loss rate over all for archery. Judging from the skepticism on here when I said that upuntil this year I'd never lost a deer, that may be a good number. That being the case even the hot rods that think they can out shoot anyone are losing a fair number of deer. My experience is that I would have to expect losses if I could not secure permission to recover one even if I could see it. We have a group here that provides bow hunters to metro locations that hold special seasons to deal with the over population. We have an area of more than 500 square miles with a population so high that there is no limit on antlerless deer. A lot of that isn't dense residential, but a lot of it is quite so. I went through the process to be part of that but decided against it because of that unpredictability factor.