I shoot the same make of bow, but different models. I shoot an elite victory for target, a synergy for hunting, and a e35 for 3d. I have the target and 3d bow set up with the same sight, rest, peep height, and nock point, just different power lens's. The one difference is the grip. I try to get them as similar as possible, but as any victory shooter knows its pretty tough to get a grip exactly like that! Its hands down my favorite grip.. I use shrewd grips for the other bows that dont have an integrated grip. As far as being able to shoot them back to back, not a problem. Being in shape is key, muscle memory plays a big role for sure as previosly stated, and form is very important.
Now when i go to my hunting rig, the synergy, things change a little. I use a different sight, but still shoot a single pin with round scope, w/o a lens. The rest is a pro v so thats different too but still limb driven. and the draw cycle / holding weight is different as well. All in all the bows are very similar but different in there own ways, and i can honestly say that i can shoot each one very well. One thing i will say, is the hold of the bow. My target rig with a 27" front bar and 15" side bar holds very different compared to my 10" front bar and 8" side bar on my synergy thats for sure! But i can still hammer those x's
All 3 bows however, have the same peep height, the same nock point. I just like different letoff for different situations, hence the use / owning of more than just a couple of bows. I like to set my bows up and leave them that way.