What are some oddities with feathers I would need to consider?
I use both feathers and various vanes. Neither will compensate for poor tuning, poor form, punching the release, etc. I have yet to see either make up for a bad shot on game. Feathers are lighter, if you believe in the FOC thing, and they might make a 5fps difference, if that seems important. Feathers
are way less problematic if you have a bit of rest contact you can't seem to tune out, so if you like big fletch with lots of helical or offset, they will help with that. Feathers will also take a beating on a single spot target, vanes don't shoot that great with holes in 'em. I like them for indoor shoots for that reason.
Otherwise, try both, and shoot them side by side for a week or so. You'll likely not be much impressed either way.