Tough one. I think if you know how and where to put your arrow, go for it. I had this buck head on this year. He, and 4 Does, had me pegged. Ranged him at 67 yards, put my pin right in the left of his right arm, and nailed it. He stumbled 30 yards down to his death. Tore his heart apart, 1 lung cut open, and the insides looked like it came out of a blender.
The blood was easy to see, not that you needed blood to find him.
67 Yards
70lb 29" Mathews DXT-Gold Tip 7595 ProHunters+100Gr NAP Spitfire BH's (404 Gr. Total weight) 298 FPS